Mutations in TRPC6 are a cause of autosomal dominant focal segmental glomerulosclerosis in humans.Many of these mutations are known to have a gain-of-function effect on the non-specific cation channel function of TRPC6.In vitro studies have suggested these mutations affect several signaling pathways, but in vivo studies have largely compared wild-t
Laser marking on polymer composite surfaces can be difficult to read and cause readability problems for electronic decoding equipment on production lines due to poor interaction between the laser and the fibers used to reinforce these materials.This problem can be solved with the right choice of marking parameters, resulting in savings for companie
Background: Pityriasis rosea is an acute disseminated rash of unknown etiology and prolonged duration, characterized by erythematous- squamous plaques.Despite having an ostentatious clinical picture for both the patient and family, it is self-limited and usually resolves without sequelae.Pityriasis rosea is often erroneously diagnosed as mycosis an
On 19 January 2020, an Mw6.0 earthquake occurred in Jiashi County, Xinjiang, China.This earthquake is a strong earthquake that occurred in the Kepingtage Belt.The monitoring and inversion of the co-seismic and post-earthquake will help further understand the geometry and grab pink zwei movement properties of this tectonic belt.In this study, Sentin
Spectrum data, which are usually characterized by many dimensions, such as location, frequency, time, and signal strength, present formidable challenges in terms of acquisition, processing, and visualization.In practice, a portion of spectrum data entries may be unavailable due to the interference during the acquisition process or compression durin